How Does Bpg Affect Hemoglobin?

That is, by binding to hemoglobin, 2,3-BPG decreases hemoglobins affinity for oxygen, thereby shifting the entire oxygen-binding curve to the right side. This is what allows the hemoglobin to act as an effective oxygen carrier in the body, unloading about 66% of oxygen to exercising tissue.

2,3 BPG and Hemoglobin

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Effect of 2,3-BPG on Hemoglobin

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2,3 BPG and Hb

HbA #HbF #ODC.